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Connect evidence
Align strain, seed, feed, oxygen and off-gas measurements with fermentation phases.
01
← All modalities
BACTERIAL · YEAST
Microbial and precision fermentation
Connect strain, substrate and inoculum history with fermentation measurements and product outcomes. Compare growth, feed, oxygen demand and metabolic behavior to investigate the constraints shaping productivity.
Bacterial · YeastMicrobial and precision fermentation
OUTCOMES TRACKEDBiomasstiterproductivity
MODALITY-SPECIFIC PROCESS INTELLIGENCE
Link microbial kinetics to feed, oxygen and scale.
01Strain & seed
02Fermentation
03Recovery
04Product analysis
FOCUS AREA · Strain & seed
Strain and process context
Carry strain identity, inoculum history, material lots and operating conditions into run comparisons.
01
EVIDENCE · MODELS · DECISIONS
Keep every conclusion connected.
Evidence in Bio Hub
- Strain, substrate and inoculum history
- Feed, oxygen, off-gas and temperature
- Biomass, metabolites and product measurements
Models in Bio Twin
- Growth and substrate-consumption kinetics
- Oxygen-demand and transport assessment
- Feed and productivity scenarios
Scientific decisions
- Compare feeding strategies
- Identify oxygen or substrate constraints
- Assess robustness across scale
Process outcomes to evaluate: Biomass · titer · productivity
SOFT SENSORS
Estimate what you cannot continuously measure.
Explore process-specific estimates of biomass, metabolites, product titer and purification performance using scientific models and available process measurements.
Explore BioMedAna Soft Sensors ↗EXAMPLE INVESTIGATION
Is a productivity change driven by feeding, biology or an oxygen constraint?
02/ 04
Compare context
Compare growth, substrate and product trajectories across representative runs.
02
03/ 04
Evaluate explanations
Assess potential oxygen-transfer and metabolic limitations with the relevant process model.
03
04/ 04
Review next steps
Recommend the measurements or experiments needed to distinguish the competing explanations.
04
Bio Agents can coordinate the scientific work across evidence and models, while Bio OS preserves governance and human review. The configured workflow determines which tasks and models are available.
Bring us this process challenge ↗EVALUATION & SCOPE
Make the demonstration specific.
Specify the organism, substrate, product and operating range. Transport constraints, overflow metabolism and model parameters must be evaluated for the process and scale under consideration.
What evidence should we bring?
Strain, substrate and inoculum history. Feed, oxygen, off-gas and temperature. Biomass, metabolites and product measurements. Include the process question, relevant run context and the analytical methods used to assess the outcome.
How do models support the workflow?
Growth and substrate-consumption kinetics. Oxygen-demand and transport assessment. Feed and productivity scenarios. Scope and evaluation criteria are defined for your process, data and intended decision.
What should we validate before using the results?
Specify the organism, substrate, product and operating range. Transport constraints, overflow metabolism and model parameters must be evaluated for the process and scale under consideration.
EXPLORE OTHER MODALITIES
ENTERPRISE USE CASE
Separating fermentation productivity loss from recovery loss
An enterprise investigation reconciling assay basis, production-phase accounting and recovery performance across a fermentation network.
Explore the complete use case ↗